Abstract
Six of 14 patients receiving a sustained release papaverine preparation developed abnormal liver function tests. One patient had jaundice and another abnormal liver histology on a biopsy specimen. This is only the third report of impaired liver function following the administration of papaverine--a drug which has been used in clinical medicine for over 100 years.
Publication types
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Case Reports
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Clinical Trial
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Controlled Clinical Trial
MeSH terms
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Aged
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Chemical and Drug Induced Liver Injury*
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Clinical Trials as Topic
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Delayed-Action Preparations
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Double-Blind Method
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Female
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Humans
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Liver / pathology
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Liver Diseases / pathology
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Liver Function Tests
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Male
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Papaverine / adverse effects*
Substances
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Delayed-Action Preparations
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Papaverine