Capillary embolization with Ethibloc: new embolization concept tested in dog kidneys

AJR Am J Roentgenol. 1981 Dec;137(6):1163-8. doi: 10.2214/ajr.137.6.1163.

Abstract

Collateral vessels in tumors and arteriovenous malformations limit the effectiveness of therapeutic embolization. Capillary propagation of embolization media represents a possible solution of the problem. Embolization with Ethibloc (Hamburg-Norderstedt), a vegetable protein dissolved in alcohol, was performed in 15 renal arteries of dogs. Three embolized kidneys were completely resorbed, and four kidneys showed complete necrosis microscopically. Ethibloc in combination with 40% glucose guarantees homogenous embolization of the entire arterial bed including the capillaries. No complications were observed in other organs.

MeSH terms

  • Animals
  • Capillaries
  • Diatrizoate*
  • Dogs
  • Drug Combinations
  • Embolization, Therapeutic*
  • Fatty Acids*
  • Kidney / blood supply*
  • Kidney Neoplasms / blood supply
  • Propylene Glycols*
  • Proteins*
  • Renal Artery
  • Renal Artery Obstruction / etiology
  • Zein*

Substances

  • Drug Combinations
  • Fatty Acids
  • Propylene Glycols
  • Proteins
  • Diatrizoate
  • Zein
  • alcoholic prolamine solution