HLA-DR4 antigen and IgA nephropathy

Tissue Antigens. 1980 Nov;16(5):405-10. doi: 10.1111/j.1399-0039.1980.tb00322.x.

Abstract

HLA-A, B and DR antigens were tested in 45 unrelated patients with IgA nephropathy (Berger's disease). A significant association with HLA-DR4 was noted. An unusual finding was a secondary association with the A2-B12 antigen combination.

MeSH terms

  • Histocompatibility Antigens Class II*
  • Humans
  • Immunoglobulin A*
  • Kidney Diseases / genetics
  • Kidney Diseases / immunology*
  • Kidney Glomerulus / pathology
  • Lymphocytes / immunology

Substances

  • Histocompatibility Antigens Class II
  • Immunoglobulin A