[Pharmacologic evaluation of penicillin in children with meningococcal meningitis]

An Esp Pediatr. 1983 Jan;18(1):5-9.
[Article in Spanish]

Abstract

Levels of penicillin both in blood and CSF are determined in 11 children with meningococcal meningitis. Authors compare these values with MIC. The therapeutic pattern was 500.000 Ul/Kg/day of benzylpenicillin, in six doses, with a single initial doses of 200.000 Ul/Kg. The results recommend not to use a lower doses in order to assure a permanently efficient penicillin concentration.

Publication types

  • English Abstract

MeSH terms

  • Cerebrospinal Fluid Proteins / analysis
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Male
  • Meningitis, Meningococcal / blood
  • Meningitis, Meningococcal / cerebrospinal fluid
  • Meningitis, Meningococcal / drug therapy*
  • Penicillin G / administration & dosage
  • Penicillin G / analysis
  • Penicillin G / therapeutic use*
  • Time Factors

Substances

  • Cerebrospinal Fluid Proteins
  • Penicillin G