Therapeutic effect of vincristine, adriamycin and prednisolone (VAP) in angioimmunoblastic lymphadenopathy (AIL)

Cancer Chemother Pharmacol. 1983;10(3):221-2. doi: 10.1007/BF00255768.

Abstract

Five patients, three males and two females, with angioimmunoblastic lymphadenopathy (AIL) are described. The two who received steroids had no response and died 2 and 6 months later. The three patients who received vincristine, adriamycin and prednisolone (VAP) went into remission early and are still in remission with a follow-up of 22-35 months. It is concluded that VAP is effective therapy in AIL.

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols*
  • Doxorubicin / administration & dosage*
  • Doxorubicin / adverse effects
  • Drug Therapy, Combination
  • Female
  • Follow-Up Studies
  • Humans
  • Immunoblastic Lymphadenopathy / drug therapy*
  • Male
  • Middle Aged
  • Prednisolone / administration & dosage*
  • Prednisolone / adverse effects
  • Vincristine / administration & dosage*
  • Vincristine / adverse effects

Substances

  • Vincristine
  • Doxorubicin
  • Prednisolone

Supplementary concepts

  • VAP protocol