Methacholine inhalation and Gm allotypes in familial asthma

J Asthma. 1984;21(1):1-8. doi: 10.3109/02770908409077392.

Abstract

In this paper, we confirmed previous studies where the results showed an incomplete genetic predisposition to allergic asthma. Our results also showed that by using the degree of sensitivity to methacholine and Gm allotypes one can obtain a better characterization than presently available of individual susceptibility to asthma in a familial setting.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Asthma / genetics*
  • Asthma / immunology
  • Bronchial Provocation Tests
  • Child
  • Female
  • Humans
  • Immunoglobulin Allotypes / genetics*
  • Immunoglobulin G*
  • Male
  • Methacholine Compounds* / administration & dosage
  • Middle Aged
  • Pedigree
  • Phenotype

Substances

  • Immunoglobulin Allotypes
  • Immunoglobulin G
  • Methacholine Compounds