[Quaternary salts of aminoethyl-p-aminobenzoates and aminoethyl-p-aminobenzamides. Synthesis and pharmacologic activity]

Abstract

A series of quaternary salts of aminoethyl-p-aminobenzoates and aminoethyl-p-aminobenzamides was synthesized starting from 4-hydroxy-3-carbomethoxy benzoic acid. Pharmacological tests of these compounds show significant spasmolytic activity: in a few cases this was also selective, but at the same time bioavailability was low.