The endocrine action of several applications of acupuncture is discussed. These hormonal actions are well known to present-day medicine. A research on the action of 6 RP on the estrogen hormones was carried out. Doses were given of plasmatic 17-beta-estradiol before and after the application of 6 RP. A Radioimmunologic Assay (RIA) was performed and the research conducted using a double blind method. The results lead to believe that the application of 6 RP causes the rise of the plasmatic rate of 17-beta-estradiol.