Primary central (medullary) fibrosarcoma of bone

Semin Diagn Pathol. 1984 Aug;1(3):185-98.

Abstract

Eighty cases of primary fibrosarcoma of bone from the Rizzoli Institute are reviewed. There was a slight male predominance with a wide patient age distribution. Roentgenologically, low grade fibrosarcomas had generally well-defined margins and a "soap-bubble" appearance. High grade tumors appeared permeative and more aggressive. Histologically, the majority of tumors were high grade (3 and 4). Prognosis correlated well with the grade of the tumor. The 10-year survival rate was 83% for low grade sarcomas and 34% for high grade tumors. Local recurrence was a bad prognostic sign.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bone Neoplasms / diagnosis*
  • Bone Neoplasms / mortality
  • Bone Neoplasms / surgery
  • Child
  • Child, Preschool
  • Female
  • Fibrosarcoma / diagnosis*
  • Fibrosarcoma / mortality
  • Fibrosarcoma / secondary
  • Fibrosarcoma / surgery
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / epidemiology
  • Prognosis