The electric discharge of Torpedo M. can be considered as an index of the metabolic activity of the electric lobe of C.N.S. In groups of 10 Torpedoes the electric charge was measured: the mechanical stimulus was obtained by the falling of different weights from a determinate height. The experiment was then repeated in conditions of hypoxia: a fall of the electric discharge values was observed. The experiment was also carried out considering the time: after 14 hours the condition of anoxia occurred.