The aim of this study was to investigate the functional role of the cortical projections to gracile nucleus. In unanesthetized cats single nuclear units projecting to the thalamus were tested for microstimulation of cortical foci (area 4) able to evoke single joint movements in contralateral hindlimb. A very significant percentage of gracile cells was influenced, very often in excitatory manner, if their receptive field was overlaying or very close to the joint controlled by a given cortical focus. Conversely, when the location of the receptive field was more distant, the percentage of responses and the incidence of excitatory effects decreased, inhibitions occurring more frequently. From a functional point of view, such an organization of the cortico-gracile control could be effective in modulating transmission of exteroceptive information from the region of the motor target (facilitation) as well as from adjacent ones (suppression). This arrangement could provide an higher resolution of afferent messages, in relation with the cortically induced movements.