A low intensity artifact appearing at the junction of perirenal fat and renal parenchyma on MR images was recently described. A symmetrical high intensity artifact is also observable on the opposite side of the kidneys as well as at the junction of the right lobe of the liver and adjacent adipose tissue. Both artifacts can be explained as exhibitions of pixel misregistration due to the difference in chemical shifts of fatty and non-fatty organs. Identification of the chemical shift misregistration effect is important since the existence of this artifact may cause erroneous diagnosis of calcification and/or fluid collections.