The relationships between temperament characteristics and first-grade teacher-student interaction were investigated. It was hypothesized that the temperament characteristics of Adaptability and Approach/Withdrawal would be potent predictors of teacher-student interactions since they had been found previously to be strong predictors of children's emotional and behavioral adjustment to school. The teachers of 105 first-grade children completed temperament questionnaires during the early part of the academic year, and their interactions with the children were observed soon thereafter. The teacher temperament ratings were factor-analyzed, and regression models were generated to predict classroom interactions. The study's hypothesis was supported, and three separate temperament dimensions were found to be predictive of classroom interactions. Suggestions are made for future extensions of the findings.