2 patients are described in whom the occurrence of central papillary atrophy of the tongue (CPA) was concurrent with gonococcal stomatitis. The significance of this finding is discussed in an attempt to highlight the fact that, in many patients, infectious processes may be responsible for the production of CPA. Previous reports combining gonococcal stomatitis and central papillary atrophy of the tongue were not found during a thorough review of the world literature.