Twenty-two own cases are presented in order to describe the clinical manifestations and therapy, especially the postoperative radiotherapy, in case of carcinomas of the upper urinary tract. The authors agree with literature to recommend a high voltage radiotherapy with 45 Gy to the regional lymph node groups and with 50 to 55 Gy to the former tumor region in case of all tumors with infiltrating growth, of demonstrated lymph node metastases and of subtotally removed primary tumors. Radiotherapy should become an essential part of the therapeutic conception for carcinomas of the renal pelvis and of the ureter because of the nearly complete absence of side effects and the small rate of local recurrences.