The paper is concerned with the main stages of scientific activity of R.V. Chagovets (1904-1982). Member Academy of Sciences of the Ukrainian SSR in the field of biochemistry of muscles, metabolism and biochemical functions of vitamins and their derivatives. The creative heredity of the scientist served as a theoretical ground of the present-day vitaminology, base for development of the nutrition theory, practical recommendations and suggestions in public health and husbandry opened the pathways for experimental solution of the problems concerning vitamin and coenzyme metabolism regulation, elucidation of molecular mechanisms of vitamin and coenzyme functioning in the cell.