Does casomorphin have a functional role?

FEBS Lett. 1984 Apr 9;169(1):53-6. doi: 10.1016/0014-5793(84)80288-4.

Abstract

Degradation of buffalo beta-casein by various physiological enzymes was studied. Digestion with gastric and pancreatic proteases plus leucine aminopeptidase did not release casomorphins but a putative precursor (procasomorphin) which was further digested by brush border peptidases into peptides differing from casomorphins.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids / analysis
  • Animals
  • Caseins / metabolism
  • Chromatography, High Pressure Liquid
  • Endorphins / metabolism*
  • Gastric Juice / enzymology
  • Leucyl Aminopeptidase / metabolism
  • Microvilli / enzymology
  • Pancreatic Juice / enzymology
  • Peptide Fragments*
  • Peptide Hydrolases / metabolism
  • Protein Precursors / metabolism
  • Rabbits

Substances

  • Amino Acids
  • Caseins
  • Endorphins
  • Peptide Fragments
  • Protein Precursors
  • beta-casomorphin 7
  • Peptide Hydrolases
  • Leucyl Aminopeptidase