Ceftazidime and cefamandole in the treatment of pneumonia

J Antimicrob Chemother. 1983 Jul:12 Suppl A:27-30. doi: 10.1093/jac/12.suppl_a.27.

Abstract

Fifty-nine community-acquired pneumonias were treated in a randomized double blind trial with cefamandole or ceftazidime. A prospective scoring system was used to define severity. This made use of basic clinical data, associated diseases, white blood count, blood gases and chest radiographs. There were no serious side-effects from the drugs. There were two deaths and six failed treatment. The scoring system which defined an 'ill group' showed as good a response of these ill patients to the new cephalosporin, ceftazidime as to cefamandole.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Cefamandole / adverse effects
  • Cefamandole / therapeutic use
  • Ceftazidime
  • Cephalosporins / adverse effects
  • Cephalosporins / therapeutic use*
  • Clinical Trials as Topic
  • Double-Blind Method
  • Female
  • Fever / chemically induced
  • Humans
  • Injections, Intravenous / adverse effects
  • Male
  • Middle Aged
  • Phlebitis / etiology
  • Pneumonia / drug therapy*
  • Random Allocation

Substances

  • Cephalosporins
  • Cefamandole
  • Ceftazidime