During angiographic placement of an intra-arterial hepatic catheter, a spasm was encountered in the proper hepatic artery. Subsequent angiography, however, revealed normal arteries. Tc-99m MAA intra-arterial infusion was then performed which showed a hepatic artery spasm. Twenty-four hours after the initial hepatic arterial spasm, a repeat injection of Tc-99m MAA revealed that the spasm was no longer present and, therefore, that intra-arterial chemotherapy could be administered.