Abstract
The effect of formiat was tested in erythrocytes of mice damaged by oxidisation. Decrease of Heinz's bodies, stabilisation of reduced glutathion, and increase of enzyme activities by referring to an example of superoxidismutase could be identified as a positive effect. Possibilities of formiat reactions in the metabolism of red blood cells are discussed.
MeSH terms
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Animals
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Erythrocytes / drug effects*
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Erythrocytes / metabolism
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Formates / pharmacology*
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Formates / therapeutic use
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Glutathione / blood
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Heinz Bodies / drug effects
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In Vitro Techniques
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Malaria / drug therapy
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Male
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Mice
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Oxidation-Reduction
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Plasmodium berghei
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Superoxide Dismutase / blood
Substances
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Formates
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formic acid
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Superoxide Dismutase
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Glutathione