Surgical approaches to cholangiocarcinoma at confluence of hepatic ducts

Lancet. 1984 Jan 14;1(8368):66-70. doi: 10.1016/s0140-6736(84)90002-3.

Abstract

Analysis of the surgical management of 94 consecutive patients with carcinoma at the confluence of the hepatic ducts showed that 20% of them (or 60% of those thought, after comprehensive pre-operative investigation, to have resectable lesions) underwent tumour resection--6 local resections and 12 liver resections. The 30-day hospital mortality was 11% and mean duration of survival was 17 months (7 patients are still alive, with a mean survival of 22.2 months). The quality of life was also much improved after resection. In patients treated with palliative surgery the hospital mortality was 33% and the mean survival was 8.5 months. The results support the treatment of bile-duct carcinoma at the hilum of the liver by resection and suggest that the use of drainage techniques, whether employed surgically or non-surgically, be reserved until the possibility of treatment by resection has been fully considered.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoma, Bile Duct / complications
  • Adenoma, Bile Duct / mortality
  • Adenoma, Bile Duct / surgery*
  • Adult
  • Aged
  • Bile Duct Neoplasms / complications
  • Bile Duct Neoplasms / mortality
  • Bile Duct Neoplasms / surgery*
  • Cholestasis / etiology
  • Drainage / methods
  • Female
  • Hepatic Duct, Common* / surgery
  • Humans
  • Male
  • Methods
  • Middle Aged
  • Palliative Care
  • Quality of Life