Morphology of primate's dopaminergic amacrine cells as revealed by TH-like immunoreactivity on retinal flat-mounts

Brain Res. 1984 Mar 12;295(1):145-53. doi: 10.1016/0006-8993(84)90825-4.

Abstract

Dopaminergic (DA) cells have been revealed by immunohistochemical localization of tyrosine hydroxylase in the retina of cynomolgus monkey, chimpanzee and human. The DA neurons were visualized in cross-sections as well as in flat-mounts of retina. The comparison revealed a striking morphological similarity between the DA neurons in the three species. When observed in flat-mounts, they were of stellate type; when observed in cross-sections, except for a few displaced cells, they were unistratified amacrine cells branching in the outermost sublayer of the inner plexiform layer. Observations in sections suggested the existence of DA-interplexiform cells in ape and human retinas.

MeSH terms

  • Animals
  • Dopamine / metabolism*
  • Fluorescent Antibody Technique
  • Histocytochemistry
  • Humans
  • Macaca fascicularis
  • Neurons / enzymology
  • Pan troglodytes
  • Retina / cytology
  • Retina / enzymology*
  • Tyrosine 3-Monooxygenase / metabolism*

Substances

  • Tyrosine 3-Monooxygenase
  • Dopamine