A useful definition of status asthmaticus is an attack which, in the physician's judgment, remains sufficiently severe following routine outpatient management to warrant admission to the hospital. Initial evaluation requires a careful history and physical and mental status examination, as well as arterial blood gas analysis. General supportive measures, oxygen and intravenous fluids are established, followed by the cornerstone of therapy, intravenous aminophylline. The second essential component is corticosteroids. Aerosolized bronchodilators and oral beta 2-adrenergic drugs are useful adjuncts.