PIP: The authors examined the effect of 3 oral contraceptives (OCs) (Bisecurin, Ovidon, and Rigevidon) on serum lipids, gamma glutamyl transpeptidase, and D-glutaric acid elimination. After 3-9 months of this medical contraception the two with the highest hormonal content significantly increased the serum cholesterol and the BLP levels. Neither one influenced the level of serum triglycerides. All significantly increased the serum level of gamma-glutamyl transpeptidase. The elimination of D-glutaric acid was also augmented. They did not find any correlation between the parameters of enzyme induration and lipid metabolism due to the taking of OCs.