Hypercortisolism

Abstract

The diagnostic evaluation of a patient with hypercortisolism should progress through screening and then confirmatory hormonal measurements. However, tests of the hypothalamic-pituitary-adrenal axis to predict the cause of hypercortisolism always should be viewed as providing supportive data, as exceptions that occur limit the usefulness of these tests. Familiarity with the diagnostic errors of the procedures is essential.