Comparative mutagenicity of two chemosterilants, tepa and hempa, in sperm of Bracon hebetor

Science. 1966 Nov 18;154(3751):915-7. doi: 10.1126/science.154.3751.915.

Abstract

In an assessment of the mutagenic efficiency of the alkylating agent, tepa, and its nonalkylating analog, hempa, both chemicals induced a high frequency of recessive lethal mutations in the sperm of the parasitic wasp, Bracon hebetor Say (Habrobracon), although tepa was the more efficient mutagen.

Publication types

  • Comparative Study

MeSH terms

  • Alkylating Agents / pharmacology*
  • Animals
  • Chemosterilants / pharmacology
  • Female
  • Genes, Lethal
  • Genes, Recessive
  • Infertility, Male / chemically induced*
  • Insecta / drug effects*
  • Male
  • Mutagens / pharmacology*
  • Mutation*
  • Spermatozoa / drug effects

Substances

  • Alkylating Agents
  • Chemosterilants
  • Mutagens