Comparative study of two anti-ulcerogenic drugs--glaziovine and sulpiride

Arzneimittelforschung. 1978;28(11):2119-21.

Abstract

The anti-ulcer effect of glaziovine, a major psychotropic alkaloid isolated from Ocotea glaziovii (Laureaceae) and belonging to a new chemical class, has been studied in different types of experimentally induced ulcers in the guinea-pig and the rat. The effect of glaziovine was compared with that of sulpiride.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Anti-Ulcer Agents*
  • Aporphines / pharmacology*
  • Female
  • Guinea Pigs
  • Histamine / pharmacology
  • Male
  • Pylorus / physiology
  • Rats
  • Reserpine / pharmacology
  • Restraint, Physical
  • Serotonin / pharmacology
  • Stomach Ulcer / chemically induced
  • Stomach Ulcer / physiopathology
  • Sulpiride / pharmacology*

Substances

  • Anti-Ulcer Agents
  • Aporphines
  • Serotonin
  • Sulpiride
  • Histamine
  • Reserpine