Abstract
The anti-ulcer effect of glaziovine, a major psychotropic alkaloid isolated from Ocotea glaziovii (Laureaceae) and belonging to a new chemical class, has been studied in different types of experimentally induced ulcers in the guinea-pig and the rat. The effect of glaziovine was compared with that of sulpiride.
MeSH terms
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Animals
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Anti-Ulcer Agents*
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Aporphines / pharmacology*
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Female
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Guinea Pigs
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Histamine / pharmacology
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Male
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Pylorus / physiology
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Rats
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Reserpine / pharmacology
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Restraint, Physical
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Serotonin / pharmacology
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Stomach Ulcer / chemically induced
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Stomach Ulcer / physiopathology
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Sulpiride / pharmacology*
Substances
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Anti-Ulcer Agents
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Aporphines
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Serotonin
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Sulpiride
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Histamine
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Reserpine