Mutagenic action of N-methyl-N'-nitro-N-nitrosoguanidine on Gaffkya tibisci at alkaline pH

Abstract

Good yields of mutants were obtained by incubating cells of Gaffkya tibisci with N-methyl-N'-nitro-N-nitrosoguanidine in alkaline buffer. Nearly 50% of the survivors were auxotrophic mutants under the conditions described.