Abstract
1. A standardized method of objectively measuring performance during simulated car driving is described. 2. The effect of a single dose of propranolol and metoprolol were compared with placebo in two groups of patients with untreated essential hypertension. 3. Performance was similar after beta-adrenoreceptor-blocking agents or placebo. 4. Blood pressure response to stress persisted after administration of the blocking agents.
Publication types
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Clinical Trial
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Comparative Study
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Controlled Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Adult
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Automobile Driving
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Blood Pressure / drug effects
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Female
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Heart Rate / drug effects
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Humans
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Hypertension / complications
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Hypertension / physiopathology*
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Male
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Metoprolol*
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Propanolamines*
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Propranolol*
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Stress, Psychological / complications
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Stress, Psychological / physiopathology*
Substances
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Propanolamines
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Propranolol
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Metoprolol