This paper deals with a classification method for human chromosome samples. A new method is proposed based on the integrated intensity profile obtained by scanning a microphotograph of chromosome sample prepared by the banding technique. Theoretical as well as experimental investigations are made. As a means of representation, Legendre polynomial series is found suitable for describing the characteristics of the chromosome in its classification. The proposed method aims at a simplified realization of a classification system. A preliminary system is constructed which consists of a ligth-pen and a television system. The proposed system is quite simple compared with the traditional ones and still exhibits satisfactory performances in the recognition rate, number of required parameters per sample, and some other important features.