Arrhythmias in dogs associated with epinephrine and thiamylal anesthesia

Am J Vet Res. 1975 Sep;36(9):1291-7.

Abstract

Sinus tachycardia bigeminy, ventricular rhythm, ventricular tachycardia, and ventricular fibrillation are produced by relatively small intravenous doses of epinephrine in nonanesthetized dogs and in dogs anesthetized with thiamylal sodium. Origin of the abnormal beat in coupled bigeminal rhythms generated from the bundle o of His or above. Increases in arterial blood pressure may predispose to arrhythmia formation during thiamylal anesthesia.

MeSH terms

  • Anesthesia, Intravenous / adverse effects
  • Anesthesia, Intravenous / veterinary*
  • Animals
  • Arrhythmias, Cardiac / veterinary*
  • Blood Pressure / drug effects
  • Bundle of His / physiopathology
  • Cardiac Complexes, Premature / chemically induced
  • Cardiac Complexes, Premature / veterinary
  • Dog Diseases / chemically induced*
  • Dogs
  • Epinephrine / adverse effects*
  • Heart Rate / drug effects
  • Nitroglycerin / pharmacology
  • Phenylephrine / pharmacology
  • Tachycardia / chemically induced
  • Tachycardia / veterinary
  • Thiamylal / adverse effects*
  • Ventricular Fibrillation / chemically induced
  • Ventricular Fibrillation / veterinary

Substances

  • Thiamylal
  • Phenylephrine
  • Nitroglycerin
  • Epinephrine