Abstract
The human enzyme, lysosomal acid phosphatase ACP2, is expressed in nan-rodent somatic cell hybrids as a dimeric molecule. The human-rodent heteropolymer, as well as the human and rodent homopolymer, is associated with lysosomes in these cells. The genes specifying lysosomal acid phosphatase ACP(2) and LDH A are syntenic.
MeSH terms
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Acid Phosphatase / analysis
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Acid Phosphatase / biosynthesis*
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Animals
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Cell Line
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Chromosome Mapping*
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Clone Cells / enzymology
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Cricetinae
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Electrophoresis, Starch Gel
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Female
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Fibroblasts
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Genes*
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Humans
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Hybrid Cells / enzymology*
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Isoenzymes / biosynthesis*
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L-Lactate Dehydrogenase / biosynthesis
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Leukocytes
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Lysosomes / enzymology*
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Male
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Mice
Substances
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Isoenzymes
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L-Lactate Dehydrogenase
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Acid Phosphatase