Abstract
No evidence was found that either perphenazine or chlorpromazine induced chromosomal damage in patients given the drugs. These results were reached independently at two separate laboratories; earlier reports of possible adverse cytogenetic effects of these drugs can probably be discounted.
Publication types
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Clinical Trial
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Controlled Clinical Trial
MeSH terms
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Adult
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Chlorpromazine / adverse effects*
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Chlorpromazine / pharmacology
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Chromosome Aberrations*
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Chromosomes / drug effects*
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Clinical Trials as Topic
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Humans
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Male
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Middle Aged
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Mitosis / drug effects
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Perphenazine / adverse effects*
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Perphenazine / pharmacology
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Statistics as Topic
Substances
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Perphenazine
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Chlorpromazine