[Effect of glycerin on several indices of intracranial hemodynamics and the electroencephalogram of wakeful cats with experimental intracerebral hemorrhage]

Farmakol Toksikol. 1979 Mar-Apr;42(2):128-32.
[Article in Russian]

Abstract

An intravenous infusion of glycerin to cats 24-48 hours after an intracerebral hemorrhage contributes to normalization of the EEG, Intensifies the local blood flow in the visual cortex, thalamus and reticular formation of the midbrain in both hemispheres (predominantly in the regions of the right affected hemisphere). The drug produces a fall in the absolute values of the intracranial pressure without its secondary rise after infusion is discontinued and causes a moderate rise of the perfusion pressure. The intravenous infusion of glycerin is more effective than its single injection.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Cats
  • Cerebral Cortex / blood supply
  • Cerebral Hemorrhage / drug therapy*
  • Cerebral Hemorrhage / physiopathology
  • Cerebrovascular Circulation*
  • Electroencephalography
  • Female
  • Glycerol / administration & dosage
  • Glycerol / therapeutic use*
  • Injections, Intravenous
  • Intracranial Pressure
  • Male
  • Reticular Formation / blood supply
  • Thalamus / blood supply

Substances

  • Glycerol