Factors affecting neonatal jaundice

Arch Dis Child. 1979 Feb;54(2):111-5. doi: 10.1136/adc.54.2.111.

Abstract

Plasma bilirubin was estimated on 690 term infants on about the 6th day of life. Perinatal factors were recorded and the results analysed. Hyperbilirubinaemia was defined as a level greater than 205 micromol/1 (12 mg/100 ml) and this was present in 20% of cases. Three factors--epidural analgesia, breast feeding, and poor weight recovery--showed highly significant associations with jaundice. The relative importance of these is discussed and compared with recent reports. Induction of labour, for reasons other than postmaturity, and a gestational age less than 39 weeks showed a slightly increased incidence of jaundice. There was no correlation with other factors tested including oxytocic drug administration. Despite the high incidence (20%) of hyperbilirubinaemia, only 2.5% infants needed treatment and none required exchange transfusion. Radical changes in obstetric management or infant feeding are not indicated.

MeSH terms

  • Anesthesia, Epidural / adverse effects
  • Body Weight
  • Breast Feeding
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Jaundice, Neonatal / etiology*
  • Labor, Induced / adverse effects
  • Oxytocin / adverse effects
  • Pregnancy
  • Prospective Studies

Substances

  • Oxytocin