IgD myeloma: immunology and ultrastructure

Ann Clin Lab Sci. 1978 May-Jun;8(3):209-18.

Abstract

A case of multiple myeloma producing IgD-M component with light chains of lambda type is reported. It involved the skeleton and was complicated by compression of the spinal cord and massive extension to the pleura. The urine contained lambda Bence Jones protein. Under the electron microscope, the neoplastic plasma cells showed dissociation between nuclear and cytoplasmic maturation.

MeSH terms

  • Aged
  • Bence Jones Protein / urine
  • Humans
  • Immunoglobulin D / metabolism*
  • Immunoglobulin lambda-Chains / metabolism
  • Male
  • Multiple Myeloma / classification
  • Multiple Myeloma / immunology*
  • Multiple Myeloma / ultrastructure
  • Myeloma Proteins / metabolism*
  • Receptors, Antigen, B-Cell / metabolism

Substances

  • Immunoglobulin D
  • Immunoglobulin lambda-Chains
  • Myeloma Proteins
  • Receptors, Antigen, B-Cell
  • Bence Jones Protein