Electrn microscopic observations on virus-like particles associated with SH antigen

J Virol. 1970 Nov;6(5):685-9. doi: 10.1128/JVI.6.5.685-689.1970.

Abstract

The structural aspects of SH antigen-containing particles were investigated. These studies confirmed the existence of a large spherical particle (ca. 43 nm) and smaller (ca. 20 nm) rod- and sphere-shaped particles. The large particle consists of an outer and inner membrane and a core of "nucleic acid" as seen by positive staining techniques. The outer membrane of the large particle appears to be similar to that of the 20-nm diameter spheres and rods known to possess the SH antigen.

MeSH terms

  • Acute Disease
  • Antigens*
  • Carrier State / immunology
  • Carrier State / microbiology
  • Chronic Disease
  • Hepatitis B / immunology
  • Hepatitis B / microbiology
  • Hepatitis B virus* / immunology
  • Hepatitis B virus* / isolation & purification
  • Humans
  • Microscopy, Electron*
  • Phosphotungstic Acid
  • Potassium Permanganate
  • Staining and Labeling
  • Uranium

Substances

  • Antigens
  • Potassium Permanganate
  • Phosphotungstic Acid
  • Uranium