Abstract
The influence of preparation methodology and storage conditions on pH and procaine stability, in a cardioplegic solution, was studied. A solution prepared with carbon dioxide in the head space and stored at -10 degrees C showed acceptable stability.
MeSH terms
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Bicarbonates / analysis*
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Calcium Chloride / analysis*
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Chromatography, High Pressure Liquid
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Drug Stability
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Half-Life
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Heart Arrest, Induced*
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Hydrogen-Ion Concentration
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Magnesium / analysis*
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Potassium Chloride / analysis*
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Procaine / analysis*
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Sodium Chloride / analysis*
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Time Factors
Substances
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Bicarbonates
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St. Thomas' Hospital cardioplegic solution
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Sodium Chloride
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Procaine
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Potassium Chloride
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Magnesium
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Calcium Chloride