[NMR tomography of excised human lymph nodes]

Med Radiol (Mosk). 1985 May;30(5):49-53.
[Article in Russian]

Abstract

The paper is concerned with the potentialities of the NMR-tomography technique (1H) for metastructure studying of the biopsied human lymph nodes both uninvolved and affected by tumor. Tomography was performed at 200 MHz using the Bruker CXP-200t mini-tomograph. Spin-echoes sequence and projection-reconstruction technique was employed. Spatial resolution was about 0.1 mm. Images of the uninvolved lymph nodes permitted one to detect the structure of the lymph nodes. NMR-imaging of unenlarged lymph nodes enabled one to localize the region of initial metastases. The reconstruction of various groups of spin-echo signals permitted a more precise detection of the regions differed in their spin-spin magnetic relaxation times T2 of protons in 1 mm slice. It may be assumed that the distinction in T2-relaxation rates of the normal and abnormal tissues displays an effective means to detect a pathological region using high-field tomography.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Female
  • Humans
  • In Vitro Techniques
  • Lymph Nodes / anatomy & histology
  • Lymphatic Metastasis / diagnosis*
  • Magnetic Resonance Spectroscopy*
  • Male
  • Melanoma / secondary
  • Middle Aged
  • Neck
  • Thyroid Neoplasms / secondary