Abstract
A retrospective clinical study made to determine the course and prognosis of the disease in 51 cases of Behçet's disease, with a follow-up of at least one year (average five years, range 1 to 15 years), showed that 45% of the eyes kept visual acuities of 1/10 or less, and 44% 8/10 or better, four years after the onset of the ocular symptoms. Ten years later, some 50% of the eyes had visual acuities of 1/10 or less and 32% had acuities of 8/10 or better. In the group of patients who were treated early with chlorambucil, the eye prognosis was significantly improved.
MeSH terms
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Adolescent
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Adult
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Behcet Syndrome / diagnosis*
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Behcet Syndrome / drug therapy
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Behcet Syndrome / immunology
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Behcet Syndrome / physiopathology
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Central Nervous System Diseases / complications
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Chlorambucil / adverse effects
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Chlorambucil / therapeutic use
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Eye Diseases / complications
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Female
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HLA Antigens / analysis
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HLA-B Antigens*
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HLA-B51 Antigen
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Humans
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Male
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Middle Aged
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Prognosis
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Skin Diseases / complications
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Steroids / therapeutic use
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Stomatitis, Aphthous / complications
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Vascular Diseases / complications
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Visual Acuity / drug effects
Substances
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HLA Antigens
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HLA-B Antigens
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HLA-B5 antigen
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HLA-B51 Antigen
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Steroids
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Chlorambucil