The Widal slide agglutination test, a valuable rapid diagnostic test in typhoid fever patients at the Infectious Diseases Hospital of Jakarta

Am J Epidemiol. 1986 May;123(5):869-75. doi: 10.1093/oxfordjournals.aje.a114316.

Abstract

The Widal slide agglutination test was evaluated as a rapid diagnostic test in typhoid fever patients at the Infectious Diseases Hospital, Jakarta, Indonesia from 1980-1982. The results of the test can be available within 45 minutes of patient admission. The study showed that, among 229 patients with Salmonella typhi-positive typhoid fever and 179 control fever patients, when the Widal O antibody titer was greater than or equal to 1:20 the sensitivity was 53%, the specificity 98%, the positive predictive value 96%, and the negative predictive value 68%. A negative Widal test (O antibody titer less than 1:20) does not provide useful information, but when the O antibody titer is greater than or equal to 1:20 the clinician at the Infectious Diseases Hospital of Jakarta can be 96% certain that the patient has typhoid fever.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antibodies / isolation & purification
  • Child
  • Child, Preschool
  • Evaluation Studies as Topic
  • Female
  • Hemagglutination Tests / methods*
  • Hospitalization
  • Humans
  • Indonesia
  • Male
  • Middle Aged
  • Typhoid Fever / diagnosis*
  • Typhoid Fever / immunology

Substances

  • Antibodies