Cutaneous malignant lymphomas. A clinicopathologic study of thirty-seven cases

Acta Pathol Jpn. 1985 Sep;35(5):1181-9.

Abstract

Clinical and histological findings in 37 cases of cutaneous lymphomas other than mycosis fungoides and Sezary syndrome were investigated; there were 31 in adults and 6 in children. Cutaneous lesions were the first manifestations of the diseases in all cases, and they appeared mostly as tumors or nodules. Cytomorphologically, about a half of the cases showed proliferations of large cleaved, non-cleaved cells or immunoblasts (Group I). Eight cases showed a polymorphous appearance containing convoluted cells of various size (Group II). Five cases in children demonstrated monomorphous proliferation of uniform-sized lymphoblasts (Group III). The cytologic findings in 6 cases did not fit into any lymphoid groups (Group IV). The clinical findings observed in each group were reviewed and compared. Follow-up study revealed that the prognosis of Group I was the poorest among the four groups.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antigens, Differentiation, B-Lymphocyte
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Lymphokines / analysis
  • Lymphoma / immunology
  • Lymphoma / pathology*
  • Male
  • Middle Aged
  • Muramidase / analysis
  • Prognosis
  • Receptors, Antigen, B-Cell / analysis
  • Rosette Formation
  • Skin Neoplasms / immunology
  • Skin Neoplasms / pathology*

Substances

  • Antigens, Differentiation, B-Lymphocyte
  • Lymphokines
  • Receptors, Antigen, B-Cell
  • Muramidase