The endocrine community has witnessed significant advances in understanding and management of pheochromocytoma and paraganglioma, thanks to continuous and relentless efforts of healthcare professionals and researchers worldwide. The 6th International Symposium on Pheochromocytoma (ISP) held in Prague, Czech Republic in September 2022 brought together experts from various disciplines underscoring the importance of unity in pursuit of clinical and basic research progress in these challenging endocrine tumors (Pacak and Clifton-Bligh 2023). It also provided Endocrine-Related Cancer the unique opportunity for a special collection of articles as testament to this progress and showcasing the latest developments in clinical management and research.