Osteosarcoma with widespread metastasis in a 1-year-old crossbred rabbit

Gordon Lye; Keren Dittmer; Sarah Pemberton; Kezia Lockhart; Rachel Pollard

doi:10.1111/vru.13385

Osteosarcoma with widespread metastasis in a 1-year-old crossbred rabbit

Vet Radiol Ultrasound. 2024 May 16. doi: 10.1111/vru.13385. Online ahead of print.

Authors

Gordon Lye¹, Keren Dittmer², Sarah Pemberton², Kezia Lockhart³, Rachel Pollard⁴

Affiliations

¹ Animal Referral Centre, Auckland, New Zealand.
² School of Veterinary Science, Massey University, Palmerston North, New Zealand.
³ Care Vets, Auckland, New Zealand.
⁴ Southern Veterinary Imaging, Nelson, New Zealand.

PMID: 38757436
DOI: 10.1111/vru.13385

Abstract

A 14-month-old female spayed, small crossbred rabbit presented for assessment of a small, hard subcutaneous nodule in the right axilla. Serum biochemistry showed markedly increased serum ALP activity. A whole-body CT revealed an aggressive, monostotic osteolytic, and productive lesion within the left alveolar process of the maxilla, with erosion of the alveolar bone and secondary premolar depression. Innumerable metastatic osseous masses were present throughout the body, including cerebral, pulmonary, hepatic, subcutaneous, and skeletal muscular metastases. Postmortem findings confirmed widespread, metastatic osteosarcoma, with the primary lesion within the left maxilla.

Keywords: computed tomography; histopathology; lagomorph; metastatic; osteosarcoma; rabbit.