Vaccine Development

Pediatr Clin North Am. 2024 Jun;71(3):529-549. doi: 10.1016/j.pcl.2024.01.018. Epub 2024 Mar 12.

Abstract

This article considers ethical considerations surrounding pediatric vaccine development for pandemic preparedness, examines some historical cases of pediatric vaccines developed during past smallpox, influenza, and 2019 coronavirus disease pandemics, and discusses the current state of vaccine development for pandemic preparedness, including vaccines against smallpox/mpox, influenza, anthrax, and Ebola that are included in the US Strategic National Stockpile and vaccines being developed against priority pathogens identified by the World Health Organization.

Keywords: Anthrax; COVID-19; Ebola; Emerging infections; Influenza; Mpox; Pediatric vaccines; Smallpox.

Publication types

  • Review
  • Historical Article

MeSH terms

  • COVID-19 / epidemiology
  • COVID-19 / prevention & control
  • Child
  • Humans
  • Pandemics / prevention & control
  • United States
  • Vaccine Development*
  • Vaccines