Similarities and Differences in Functional Movement Disorders and Functional Seizures at a Tertiary Care Center: A Prospective Study

Ann Indian Acad Neurol. 2024 Mar-Apr;27(2):172-177. doi: 10.4103/aian.aian_893_23. Epub 2024 Apr 26.

Abstract

Background: Functional movement disorders (FMDs) and functional seizure (FS) are the two most important subcategories of functional neurologic disorders (FNDs).

Objectives: This study aimed to discern similarities and differences between patients with FMD and FS.

Methods: A prospective comparative study of 94 patients with FNDs (FMD = 47, FS = 47) was conducted.

Results: Tremor and pauci-kinetic attack with preserved responsiveness were the most common subtypes observed in patients with FMD and FS, respectively. A significantly higher number of patients with FMD had more than one precipitating factor (P = 0.03). Headache was significantly more common in patients with FS (P = 0.03). More patients came for follow-up in the FMD group (P = 0.01). More patients in the FS group reported "very much improvement" (P = 0.04), and "no change" was more commonly reported by the FMD group patients (P = 0.009).

Conclusion: Emotional stress was the most common precipitating factor in patients with FMD and FS. The prognosis was better in patients with FS.

Keywords: Functional movement disorder; functional seizure; tremor.