A Case of Organizing Pneumonia Resembling Lung Cancer

Clin Lab. 2024 May 1;70(5). doi: 10.7754/Clin.Lab.2023.231216.

Abstract

Background: Organizing pneumonia (OP) is a pathologic diagnosis with clinical and imaging manifestations that often resemble other diseases, such as infections and cancers, which can lead to delays in diagnosis and inappropriate management of the underlying disease. In this article, we present a case of organized pneumonia that resembles lung cancer.

Methods: We report a case of initial suspicion of pulmonary malignancy, treated with anti-inflammatory medication and then reviewed with CT suggesting no improvement, and finally confirmed to be OP by pathological biopsy taken via transbronchoscopy. A joint literature analysis was performed to raise clinicians' awareness of the diagnosis and treatment of OP.

Results: Initially, because of the atypical auxiliary findings, we thought that the disease turned out to be a lung tumor, which was eventually confirmed as OP by pathological diagnosis.

Conclusions: The diagnosis and treatment of OP requires a combination of clinical information and radiological expertise, as well as biopsy to obtain histopathological evidence. That is, clinical-imaging-pathological tripartite cooperation and comprehensive analysis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy
  • Bronchoscopy
  • Cryptogenic Organizing Pneumonia / diagnosis
  • Cryptogenic Organizing Pneumonia / diagnostic imaging
  • Cryptogenic Organizing Pneumonia / pathology
  • Diagnosis, Differential
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology
  • Lung Neoplasms* / diagnosis
  • Lung Neoplasms* / diagnostic imaging
  • Lung Neoplasms* / pathology
  • Male
  • Middle Aged
  • Organizing Pneumonia
  • Tomography, X-Ray Computed*