DNAforge: a design tool for nucleic acid wireframe nanostructures

Antti Elonen; Leon Wimbes; Abdulmelik Mohammed; Pekka Orponen

doi:10.1093/nar/gkae367

DNAforge: a design tool for nucleic acid wireframe nanostructures

Nucleic Acids Res. 2024 May 15:gkae367. doi: 10.1093/nar/gkae367. Online ahead of print.

Authors

Antti Elonen¹, Leon Wimbes^{1

2}, Abdulmelik Mohammed³, Pekka Orponen¹

Affiliations

¹ Department of Computer Science, Aalto University, Finland.
² Department of Mathematics and Computer Science, Philipps University of Marburg, Germany.
³ Department of Biomedical Engineering, San José State University, USA.

PMID: 38747339
DOI: 10.1093/nar/gkae367

Abstract

DNAforge is an online tool that provides a unified, user-friendly interface to several recent design methods for DNA and RNA wireframe nanostructures, with the possibility of integrating additional methods into the same framework. Currently, DNAforge supports three design methods for DNA nanostructures and two for RNA nanostructures. The tool enables the design, visualisation and sequence generation for highly complex wireframe nanostructures with a simple fully automated process. DNAforge is freely accessible at https://dnaforge.org/.

Abstract

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