The many faces of sickle cell disease in children: complications in the appendicular skeleton

Marcela De La Hoz Polo; Victoria E Hudson; John Adu; Subarna Chakravorty; Saira Haque

doi:10.1007/s00247-024-05913-9

The many faces of sickle cell disease in children: complications in the appendicular skeleton

Pediatr Radiol. 2024 May 14. doi: 10.1007/s00247-024-05913-9. Online ahead of print.

Authors

Marcela De La Hoz Polo¹, Victoria E Hudson², John Adu³, Subarna Chakravorty⁴, Saira Haque⁵

Affiliations

¹ Everlight Radiology, London, UK.
² Radiology Department, King's College Hospital, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK.
³ Radiology Department, St George's University Hospital, London, UK.
⁴ Department of Paediatric Haematology, King's College Hospital, King's College Hospital NHS Foundation Trust, London, UK.
⁵ Radiology Department, King's College Hospital, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK. saira.haque@nhs.net.

PMID: 38740606
DOI: 10.1007/s00247-024-05913-9

Abstract

Sickle cell disease (SCD) is a hereditary red cell disorder with clinical manifestations secondary to sickling or crescent-shaped distortion of the red blood cells. Musculoskeletal complications of SCD are often the main causes for acute and chronic morbidities in children with manifestations including osteomyelitis, osteoporosis and osteonecrosis. This article aims to familiarise the paediatric radiologist with appendicular skeletal complications of SCD in the paediatric population and their imaging appearance.

Keywords: Avascular necrosis; Complication; Infection; Musculoskeletal; Osteonecrosis; Septic arthritis; Sickle cell disease.