FDG PET/CT Findings of Primary Pulmonary Choriocarcinoma in a Postmenopausal Woman

Jun Zhang; Aisheng Dong; Yang Wang

doi:10.1097/RLU.0000000000005272

FDG PET/CT Findings of Primary Pulmonary Choriocarcinoma in a Postmenopausal Woman

Clin Nucl Med. 2024 May 9. doi: 10.1097/RLU.0000000000005272. Online ahead of print.

Authors

Jun Zhang¹, Aisheng Dong², Yang Wang³

Affiliations

¹ From the Department of Cardiothoracic Surgery, The Second Affiliated Hospital, Jiaxing University, Jiaxing, Zhejiang Province.
² Department of Nuclear Medicine, The First Affiliated Hospital of Naval Medical University.
³ Department of Pathology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.

PMID: 38739485
DOI: 10.1097/RLU.0000000000005272

Abstract

Choriocarcinomas usually occur in the genital tracts of reproductive-age women after a gestational event. Primary pulmonary choriocarcinoma is very rare. We describe FDG PET/CT findings of primary pulmonary choriocarcinoma with multiple intrapulmonary metastases in a postmenopausal woman with elevated serum beta human chorionic gonadotropin level. On FDG PET/CT, the large primary lung tumor showed intense FDG uptake (SUVmax, 46), and the small intrapulmonary metastases showed variable FDG uptake (SUVmax, 27). Primary pulmonary choriocarcinoma should be included in the differential diagnosis of FDG-avid pulmonary lesions with elevated serum beta human chorionic gonadotropin levels, including metastatic choriocarcinoma and lung cancer.